Anti-phospho-CFL1(Ser3)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-68106.60 60 µl - -

7 - 16 Werktage*

181,00 €
E-AB-68106.120 120 µl - -

7 - 16 Werktage*

287,00 €
E-AB-68106.200 200 µl - -

7 - 16 Werktage*

469,00 €
 
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a... mehr
Produktinformationen "Anti-phospho-CFL1(Ser3)"
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. Protein function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration. [The UniProt Consortium]
Schlagworte: Anti-phospho-p18, Anti-phospho-CFL, Anti-phospho-CFL1, Anti-phospho-Cofilin-1, Anti-phospho-18 kDa phosphoprotein, Anti-phospho-Cofilin, non-muscle isoform, Phospho-CFL1(S3) Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-68106

Eigenschaften

Anwendung: WB, IHC, IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: A phospho specific peptide corresponding to residues surrounding S3 of human CFL1

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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