Anti-phospho-BAD (Thr137)

Anti-phospho-BAD (Thr137)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F48671-0.08ML 80 µl - -

3 - 10 Werktage*

326,00 €
NSJ-F48671-0.4ML 400 µl - -

3 - 10 Werktage*

702,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a member of the... mehr
Produktinformationen "Anti-phospho-BAD (Thr137)"
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq]. Protein function: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. [The UniProt Consortium]
Schlagworte: Anti-phospho-BAD, Anti-phospho-BBC6, Anti-phospho-Bcl2-L-8, Anti-phospho-Bcl-2-like protein 8, Anti-phospho-Bcl-2-binding component 6, Anti-phospho-Bcl2 antagonist of cell death, Anti-phospho-Bcl2-associated agonist of cell death, Phospho-BAD Antibody (pT
Hersteller: NSJ Bioreagents
Hersteller-Nr: F48671

Eigenschaften

Anwendung: Dot Blot, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: This phospho-BAD antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT137 of human BAD.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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