Anti-phospho-BAD (Ser136)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-35-1066-50 50 µl -

3 - 11 Werktage*

574,00 €
 
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known... mehr
Produktinformationen "Anti-phospho-BAD (Ser136)"
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. Protein function: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. [The UniProt Consortium]
Schlagworte: Anti-phospho-Bad, Anti-phospho-BAD, Anti-phospho-Bbc6, Anti-phospho-Bcl-2-binding component 6, Anti-phospho-Bcl2 antagonist of cell death, Anti-phospho-Bcl2-associated agonist of cell death, Anti-phospho-Bcl-xL/Bcl-2-associated death promoter, Polyclonal
Hersteller: Abeomics
Hersteller-Nr: 35-1066-50

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Peptide sequence around phosphorylation site of serine136 (S-R-S(p)-A-P) derived from Mouse BAD.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-phospho-BAD (Ser136)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen