Anti-phospho-AKT1 (Thr308) (AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinas

Anti-phospho-AKT1 (Thr308) (AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinas
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
031756.200 200 µl - -

3 - 19 Werktage*

728,00 €
 
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in... mehr
Produktinformationen "Anti-phospho-AKT1 (Thr308) (AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinas"
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]. Applications: Suitable for use in Immunofluorescence, Dot Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Dot blot 1:100-500, Immunofluorescence: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: Anti-phospho-PKB, Anti-phospho-AKT1, Anti-phospho-PKB alpha, EC=2.7.11.1, Anti-phospho-RAC-PK-alpha, Anti-phospho-Protein kinase B, Anti-phospho-Proto-oncogene c-Akt, Anti-phospho-Protein kinase B alpha
Hersteller: United States Biological
Hersteller-Nr: 031756

Eigenschaften

Anwendung: ELISA, Dot Blot, IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Phospho-AKT1 (Thr308) Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding Thr308 of human AKT1.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-phospho-AKT1 (Thr308) (AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinas"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen