Anti-gamma-H2AX

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A300-081A-T 10 µl (10 µg) -

2 - 8 Werktage*

164,00 €
A300-081A 100 µl (100 µg) -

2 - 8 Werktage*

626,00 €
 
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.... mehr
Produktinformationen "Anti-gamma-H2AX"
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation. [The UniProt Consortium]
Schlagworte: Anti-H2AX, Anti-H2AFX, Anti-H2a/x, Anti-Histone H2AX, Anti-Histone H2A.X
Hersteller: Bethyl Laboratories
Hersteller-Nr: A300-081A

Eigenschaften

Anwendung: WB, IHC, ICC-IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse (Erwartet: bovine, dog, rabbit, guinea pig_10141, pig, rhesus monkey, gorilla, crab-eating macaque, chinese hamster, thirteen-lined ground squirrel, little brown bat)
Immunogen: synthetic peptide. The epitope recongized by A300-081A-T maps to a region surrounding phosphorylated serine 139 of human histone H2AX using the numbering given for Swiss-Prot entry P16104 (GeneID 3014)
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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