PTM-spezifische Antikörper

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Anti-phospho-IKK beta (Ser705)
Anti-phospho-IKK beta (Ser705)

Artikelnummer: NSJ-F48708-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by...
Schlagworte: Anti-phospho-IKKB, Anti-phospho-IKK2, Anti-phospho-IkBKB, Anti-phospho-IKK-B, Anti-phospho-IKBKB, Anti-phospho-NFKBIKB,...
Anwendung: DB, ELISA
Reaktivität: Human
ab 228,00 €
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Anti-phospho-TSC1 (Tyr297)
Anti-phospho-TSC1 (Tyr297)

Artikelnummer: NSJ-F48830-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. Protein function: In complex with TSC2,...
Schlagworte: Anti-phospho-TSC1, Anti-phospho-Hamartin, Anti-phospho-KIAA0243, Anti-phospho-Tuberous sclerosis 1 protein, Phospho-TSC1...
Anwendung: DB, ELISA
Reaktivität: Human
ab 228,00 €
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Anti-phospho-LIPE / HS (Ser565)
Anti-phospho-LIPE / HS (Ser565)

Artikelnummer: ARG42017.50

Protein function: In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. [The UniProt Consortium]
Schlagworte: Anti-phospho-HSL, Anti-phospho-LIPE, EC=3.1.1.79, Anti-phospho-Hormone-sensitive lipase
Anwendung: WB
Reaktivität: Human
439,00 €
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Anti-phospho-LIPE / HS (Ser563)
Anti-phospho-LIPE / HS (Ser563)

Artikelnummer: ARG42019.50

Protein function: In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. [The UniProt Consortium]
Schlagworte: Anti-phospho-HSL, Anti-phospho-LIPE, EC=3.1.1.79, Anti-phospho-Hormone-sensitive lipase
Anwendung: WB
Reaktivität: Human
439,00 €
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Anti-phospho-ATF2 (Thr52)
Anti-phospho-ATF2 (Thr52)

Artikelnummer: ARG52232.50

Protein function: Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein...
Schlagworte: Anti-phospho-HB16, Anti-phospho-ATF2, Anti-phospho-CREB2, Anti-phospho-CREB-2, Anti-phospho-Histone acetyltransferase...
Anwendung: WB
Reaktivität: Human
498,00 €
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Anti-phospho-PLK1 (Ser482 / Ser486 / Ser490)
Anti-phospho-PLK1 (Ser482 / Ser486 / Ser490)

Artikelnummer: ARG52397.50

Protein function: Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C)...
Schlagworte: Anti-phospho-plx1, Anti-phospho-Plx1, Anti-phospho-plk1, Anti-phospho-PLK-1, EC=2.7.11.21, Anti-phospho-Polo-like kinase...
Anwendung: WB
Reaktivität: Xenopus Laevis
498,00 €
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Anti-phospho-Raf1 (Ser642)
Anti-phospho-Raf1 (Ser642)

Artikelnummer: ARG52410.50

Protein function: Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic...
Schlagworte: Anti-phospho-Raf, Anti-phospho-cRaf, Anti-phospho-Raf1, Anti-phospho-Raf-1, EC=2.7.11.1, Anti-phospho-Proto-oncogene...
Anwendung: WB
Reaktivität: Rat
498,00 €
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STAT1 / Phospho STAT1 (pY701) Antibody Duo
STAT1 / Phospho STAT1 (pY701) Antibody Duo

Artikelnummer: ARG30339.1

Protein function: Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation...
Schlagworte: Anti-phospho-STAT1, Anti-phospho-Transcription factor ISGF-3 components p91/p84, Anti-phospho-Signal transducer and...
Reaktivität: Human, Mouse, Rat
542,00 €
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Anti-Acetyl CoA carboxylase 1
Anti-Acetyl CoA carboxylase 1

Artikelnummer: ARG42624.100

Protein function: Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656, PubMed:20457939, PubMed:29899443). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by...
Schlagworte: Anti-acetyl-ACC1, Anti-acetyl-ACAC, Anti-acetyl-ACC-alpha, Anti-acetyl-Acetyl-CoA carboxylase 1,...
Anwendung: IHC (paraffin), WB
Reaktivität: Human, Mouse, Rat
505,00 €
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Anti-phospho-Acetyl CoA carboxylase 1 (Ser79)
Anti-phospho-Acetyl CoA carboxylase 1 (Ser79)

Artikelnummer: ARG42625.100

Protein function: Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656, PubMed:20457939, PubMed:29899443). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by...
Schlagworte: Anti-phospho-acetyl-ACC1, Anti-phospho-acetyl-ACAC, Anti-phospho-acetyl-ACC-alpha, Anti-phospho-acetyl-Acetyl-CoA...
Anwendung: WB
Reaktivität: Human, Mouse, Rat
505,00 €
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Anti-phospho-c-Cbl (Tyr674)
Anti-phospho-c-Cbl (Tyr674)

Artikelnummer: ARG42630.100

Protein function: Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting...
Schlagworte: Anti-phospho-CBL, Anti-phospho-CBL2, Anti-phospho-Proto-oncogene c-Cbl, Anti-phospho-RING finger protein 55,...
Anwendung: FC, ICC, IF, WB
Reaktivität: Human
505,00 €
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Anti-Methylated Lysine (biotinylated)
Anti-Methylated Lysine (biotinylated)

Artikelnummer: Cay13728-400

Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of lysine involves methylation. Lysine can be methylated once,...
Anwendung: ELISA, ICC/IF, IP, WB
470,00 €
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659 von 658 Seiten