Anti-WTAP

Anti-WTAP
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A301-435A-T 10 µl (10 µg) -

2 - 8 Werktage*

164,00 €
A301-435A 100 µl (100 µg) -

2 - 8 Werktage*

588,00 €
 
Protein function: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein... mehr
Produktinformationen "Anti-WTAP"
Protein function: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724). [The UniProt Consortium]
Schlagworte: Anti-WTAP, Anti-hFL(2)D, Anti-KIAA0105, Anti-WT1-associated protein, Anti-Female-lethal(2)D homolog, Anti-Pre-mRNA-splicing regulator WTAP, Anti-Wilms tumor 1-associating protein
Hersteller: Bethyl Laboratories
Hersteller-Nr: A301-435A

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human (Erwartet: orangutan, gorilla, chimpanzee, white-tufted-ear marmoset)
Immunogen: synthetic peptide. The epitope recognized by A301-435A-T maps to a region between residue 250 and 300 of human Wilms tumor 1 associated protein using the numbering given in entry NP_004897.2 (GeneID 9589).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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