Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A302-077A-T 10 µl (10 µg) -

3 - 9 Werktage*

131,00 €
A302-077A 100 µl (100 µg) -

3 - 9 Werktage*

465,00 €
Protein function: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway.... mehr
Produktinformationen "Anti-VPS4B"
Protein function: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). [The UniProt Consortium]
Schlagworte: Anti-SKD1, Anti-MIG1, Anti-VPS4B, EC=, Anti-Protein SKD1, Anti-Cell migration-inducing gene 1 protein, Anti-Suppressor of K(+) transport growth defect 1, Anti-Vacuolar protein sorting-associated protein 4B
Hersteller: Bethyl Laboratories
Hersteller-Nr: A302-077A


Anwendung: IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human (Erwartet: Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A302-077A-T maps to a region between residue 300 and 350 of human vacuolar protein sorting 4 homolog B using the numbering given in entry NP_004860.2 (GeneID 9525).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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