Anti-VHL, CT (Von Hippel-Lindau Disease Tumor Suppressor, pVHL, Protein G7)

Anti-VHL, CT (Von Hippel-Lindau Disease Tumor Suppressor, pVHL, Protein G7)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
V2640-03K.50 50 µg - -

3 - 19 Werktage*

796,00 €
 
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing... mehr
Produktinformationen "Anti-VHL, CT (Von Hippel-Lindau Disease Tumor Suppressor, pVHL, Protein G7)"
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of VHL gene is the basis of familial inheritance of VHL syndrome. The protein is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 , Immunohistochemistry (Formalin-fixed, paraffin-embedded): 15ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hersteller: United States Biological
Hersteller-Nr: V2640-03K

Eigenschaften

Anwendung: ELISA, IHC, WB
Antikörper-Typ: Monoclonal
Klon: 52A11
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant corresponding to aa1-154 from human His-VHL, expressed in E. coli.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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