Anti-VEGI / TL1A, clone VEGI/1283

Anti-VEGI / TL1A, clone VEGI/1283
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V3348SAF-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. TNF ligand-related molecule 1 is an... mehr
Produktinformationen "Anti-VEGI / TL1A, clone VEGI/1283"
1 mg/ml in 1X PBS, BSA free, sodium azide free. TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A has been reported as a marker of poor prognosis in breast cancer. Protein function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [The UniProt Consortium]
Schlagworte: Anti-TL1, Anti-TNFSF15, VEGI / TL1A Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V3348SAF

Eigenschaften

Anwendung: WB, FC, IF, IHC
Antikörper-Typ: Monoclonal
Klon: VEGI/1283
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: A full length human recombinant protein was used as the immunogen for this TL1A antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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