Anti-VDAC1 / Porin, clone S152B-23

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG22249.50 50 µg - -

6 - 14 Werktage

439,00 €
 
Protein function: Forms a channel through the mitochondrial outer membrane and also the plasma... mehr
Produktinformationen "Anti-VDAC1 / Porin, clone S152B-23"
Protein function: Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:11845315, PubMed:18755977, PubMed:20230784, PubMed:8420959). May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed:15033708, PubMed:25296756). [The UniProt Consortium]
Schlagworte: Anti-VDAC, Anti-VDAC1, Anti-VDAC-1, Anti-hVDAC1, Anti-Porin 31HL, Anti-Porin 31HM, Anti-Plasmalemmal porin, Anti-Outer mitochondrial membrane protein porin 1, Anti-Voltage-dependent anion-selective channel protein 1
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG22249050

Eigenschaften

Anwendung: WB, IHC, ICC, IF
Antikörper-Typ: Monoclonal
Klon: S152B-23
Konjugat: No
Wirt: Mouse
Reaktivität: Human, Mouse, Rat
Immunogen: Full-length (aa. 1-283) fusion protein of Human VDAC1.Mouse: 98% identity (279/283 around aa. identical).Rat: 98% identity (279/283 around aa. identical), >60% identity with VDAC2 and VDAC3
MW: 30 kD
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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