Anti-VDAC/Porin

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-101-HB2 100 µg - -

6 - 10 Werktage*

647,00 €
 
Anti-VDAC/Porin Antibody is directed against human VDAC1/Porin1 protein.  The product was... mehr
Produktinformationen "Anti-VDAC/Porin"
Anti-VDAC/Porin Antibody is directed against human VDAC1/Porin1 protein.  The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest that this antibody would react with VDAC1/Porin1 including mouse, rat, bovine, pig, and rabbit sources based on 100% homology for the immunogen sequence. Such broad reactivity makes this antibody useful as an excellent loading control. Protein function: Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:11845315, PubMed:18755977, PubMed:20230784, PubMed:8420959). May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed:15033708, PubMed:25296756). [The UniProt Consortium]
Schlagworte: Anti-VDAC, Anti-VDAC1, Anti-hVDAC1, Anti-VDAC-1, Anti-Porin 31HL, Anti-Porin 31HM, Anti-Plasmalemmal porin, Anti-Outer mitochondrial membrane protein porin 1, Anti-Voltage-dependent anion-selective channel protein 1
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-101-HB2

Eigenschaften

Anwendung: ELISA, IHC, IFM, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Goat
Spezies-Reaktivität: human, mouse, rat
Immunogen: synthetic peptide corresponding to N-terminal portion of Human VDAC1/Porin1.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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