Anti-UPF3B

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA001800.25 25 µl -

7 - 10 Werktage*

335,00 €
ATA-HPA001800.100 100 µl -

7 - 10 Werktage*

446,00 €
 
Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop... mehr
Produktinformationen "Anti-UPF3B"
Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions. In vitro, stimulates translation, the function is independent of association with UPF2 and components of the EJC core. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 80% and to rat: 80%
Schlagworte: Anti-UPF3B, Anti-RENT3B, Anti-hUpf3B, Anti-hUpf3p-X, Anti-Nonsense mRNA reducing factor 3B, Anti-Regulator of nonsense transcripts 3B, Anti-Up-frameshift suppressor 3 homolog B, Anti-Up-frameshift suppressor 3 homolog on chromosome X
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA001800

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AKKLDKENLS DERASGQSCT LPKRSDSELK DEKPKRPEDE SGRDYRERER EYERDQERIL RERERLKRQE EERRRQKERY EKEKTFKRKE EEMKKEKDTL RDKGKKAEST ESIGSSEKTE KKEEVVKRDR IRNKDR (ATA-APrEST74305)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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