Anti-TRIM24

Anti-TRIM24
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-PACO20684.50 50 µl -

9 - 20 Werktage*

293,00 €
 
TRIM24 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human,... mehr
Produktinformationen "Anti-TRIM24"
TRIM24 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse and for use in ELISA, WB applications. TRIM24 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes. [The UniProt Consortium]
Schlagworte: Anti-RNF82, Anti-TRIM24, Anti-TIF1-alpha, EC=2.3.2.27, Anti-RING finger protein 82, Anti-E3 ubiquitin-protein ligase TRIM24, Anti-Tripartite motif-containing protein 24, Anti-Transcription intermediary factor 1-alpha
Hersteller: Assay Genie
Hersteller-Nr: PACO20684

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: Synthetic peptide of human TRIM24

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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