Anti-TRIM24

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA061717.25 25 µl -

7 - 10 Werktage*

300,00 €
ATA-HPA061717.100 100 µl -

7 - 10 Werktage*

421,00 €
 
Protein function: Transcriptional coactivator that interacts with numerous nuclear receptors and... mehr
Produktinformationen "Anti-TRIM24"
Protein function: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 91% and to rat: 80%
Schlagworte: Anti-RNF82, Anti-TRIM24, Anti-TIF1-alpha, EC=2.3.2.27, Anti-RING finger protein 82, Anti-E3 ubiquitin-protein ligase TRIM24, Anti-Tripartite motif-containing protein 24, Anti-Transcription intermediary factor 1-alpha
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA061717

Eigenschaften

Anwendung: ICC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NCAEFNEPDS EVANAGIKLE NYFEELLKNL YPEKRFPKPE FRNESEDNKF SDDSDDDFVQ PRKKRLKSIE ERQLLK (ATA-APrEST89959)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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