Anti-TrCP2 beta

Anti-TrCP2 beta
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Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-401-483 100 µg - -

1 - 9 Werktage

493,00 €
 
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3... mehr
Produktinformationen "Anti-TrCP2 beta"
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. Targets phosphorylation-dependent degradation of beta- catenin. Involved in the oxidative stress-induced a ubiquitin- mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressing through S phase and thus may function in the intra-S-phase checkpoint. Has an essential role in the control of the clock-dependent transcription via degradation of PER1 and phosphorylated PER2. Is target of human immunodeficiency virus type 1 (HIV-1) protein VPU to polyubiquitinate and deplete BST2 from cells and antagonize its antiviral action. [The UniProt Consortium]
Schlagworte: Anti-HOS, Anti-BTRCP2, Anti-FBXW11, Anti-Homologous to Slimb protein, Anti-F-box/WD repeat-containing protein 1B, Anti-F-box/WD repeat-containing protein 11, Anti-F-box and WD repeats protein beta-TrCP2
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-401-483

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Dog, Bovine, Chimpanzee, Chicken, Horse
Immunogen: synthetic peptide corresponding to a region near the N-terminal of human ßTrCP2 protein
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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