Anti-TRA-1-81, clone TRA-1-81

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG10670.50 50 µl - -

6 - 14 Werktage*

520,00 €
 
Protein function: Involved in the regulation of both adhesion and cell morphology and cancer... mehr
Produktinformationen "Anti-TRA-1-81, clone TRA-1-81"
Protein function: Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell- cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR- dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells. [The UniProt Consortium]
Schlagworte: Anti-PC, Anti-PCLP, Anti-Gp200, Anti-PODXL, Anti-PCLP-1, Anti-Podocalyxin, Anti-GCTM-2 antigen, Anti-Podocalyxin-like protein 1
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG10670

Eigenschaften

Anwendung: FC, ICC, IF
Antikörper-Typ: Monoclonal
Klon: TRA-1-81
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Human embryonal carcinoma cell line 2102Ep

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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