Anti-tPA

Anti-tPA
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R31758 100 µg - -

3 - 10 Werktage*

503,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tissue Plasminogen activator (tPA) is a... mehr
Produktinformationen "Anti-tPA"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tissue Plasminogen activator (tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. tPA is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Protein function: Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration. [The UniProt Consortium]
Schlagworte: Anti-PLAT, EC=3.4.21.68, tPA Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R31758

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: Human partial recombinant protein (AA 366-562) was used as the immunogen for this tPA antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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