Anti-TP63, clone CL3748

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-AMAb91224.25 25 µl -

7 - 10 Werktage*

240,00 €
ATA-AMAb91224.100 100 µl -

7 - 10 Werktage*

358,00 €
 
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor.... mehr
Produktinformationen "Anti-TP63, clone CL3748"
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. [The UniProt Consortium] Validated by orthogonal and standard strategies. Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 94%. Epitope specificity: MQYLPQHTIETYRQQ.
Schlagworte: Anti-p40, Anti-p51, Anti-p63, Anti-KET, Anti-CUSP, Anti-p73L, Anti-TP63, Anti-Tumor protein 63, Anti-Tumor protein p73-like, Anti-Transformation-related protein 63, Anti-Keratinocyte transcription factor KET, Anti-Chronic ulcerative stomatitis protein
Hersteller: Atlas Antibodies
Hersteller-Nr: AMAb91224

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Monoclonal
Klon: CL3748
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: CACPGRDRKA DEDSIRKQQV SDSTKNGDAF RQNTHGIQMT SIKKRRSPDD ELLYLPVRGR ETYEMLLKIK ESLELMQYLP QHTIETYRQQ QQQQHQ (ATA-APrEST88934)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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