Anti-TNFAIP1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R30362 100 µg - -

3 - 10 Werktage*

628,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor necrosis factor, alpha-induced... mehr
Produktinformationen "Anti-TNFAIP1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor necrosis factor, alpha-induced protein 1(endothelial), also known as TNFAIP1, is a human gene. The gene, present in single copy, was located in the 17q22-q23 region. This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha(TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. The protein is involved in the primary response of the endothelium to TNF. Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. [The UniProt Consortium]
Schlagworte: Anti-BACURD2, Anti-TNFAIP1, Anti-hBACURD2, Anti-Protein B12, Anti-BTB/POZ domain-containing protein TNFAIP1, Anti-Tumor necrosis factor, alpha-induced protein 1, endothelial, TNFAIP1 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R30362

Eigenschaften

Anwendung: WB, IHC (paraffin), IF, ICC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: An amino acid sequence from the N-terminus of human TNFAIP1 (NKYVQLNVGGSLYYTTVRALTRHDTM) was used as the immunogen for this TNFAIP1 antibody (100% homologous in human, mouse and rat).
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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