Anti-TJP1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA001636.25 25 µl -

Fragen Sie uns nach der Lieferzeit

156,00 €
ATA-HPA001636.100 100 µl -

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363,00 €
 
Protein function: TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight... mehr
Produktinformationen "Anti-TJP1"
Protein function: TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:7798316, PubMed:9792688). The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Necessary for lumenogenesis, and particularly efficient epithelial polarization and barrier formation. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells (PubMed:21240187). Plays an important role in podosome formation and associated function, thus regulating cell adhesion and matrix remodeling (PubMed:20930113). With TJP2 and TJP3, participates in the junctional retention and stability of the transcription factor DBPA, but is not involved in its shuttling to the nucleus. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Schlagworte: Anti-ZO1, Anti-TJP1, Anti-Zona occludens protein 1, Anti-Tight junction protein 1, Anti-Zonula occludens protein 1, Anti-Tight junction protein ZO-1
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA001636

Eigenschaften

Anwendung: ICC, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RKLYERSHKL RKNNHHLFTT TINLNSMNDG WYGALKEAIQ QQQNQLVWVS EGKADGATSD DLDLHDDRLS YLSAPGSEYS MYSTDSRHTS DYEDTDTEGG AYTDQELDET LNDEVGTPPE SAITRSSEPV RED (ATA-APrEST83050)

Datenbank Information

KEGG ID : K05701 | Passende Produkte
UniProt ID : Q07157 | Passende Produkte
Gene ID : GeneID 7082 | Passende Produkte
Protein Atlas Nr. : ENSG00000104067

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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