Anti-TAB1

Anti-TAB1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32237 100 µg - -

3 - 10 Werktage

503,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mitogen-activated protein kinase kinase... mehr
Produktinformationen "Anti-TAB1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, also called TAB1, is an enzyme that in humans is encoded by the MAP3K7IP1 gene. It is mapped to 22q13.1. The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways. This protein can interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. TAB1 also can activate the kinase activity of TAK1 by direct interaction, and it may be an important signaling intermediate between TGFB receptors and TAK1. What's more, TAB1 plays an important role in skin homeostasis, wound repair, and oncogenesis. Protein function: May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis. [The UniProt Consortium]
Schlagworte: Anti-TAB1, Anti-MAP3K7IP1, Anti-TAK1-binding protein 1, Anti-TGF-beta-activated kinase 1-binding protein 1, Anti-TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, Anti-Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, TAB1 An
Hersteller-Nr: R32237

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Rat
Immunogen: Amino acids NFVAQRLSAELLLGQLNAEHAEADVRRVLLQ of human TAB1 were used as the immunogen for the TAB1 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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