Anti-Smac / Diablo, clone RM271 (recombinant antibody)

Anti-Smac / Diablo, clone RM271 (recombinant antibody)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R20288-0.1ML 100 µl - -

3 - 10 Werktage*

580,00 €
 
Antibody in PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide. This recombinant Smac antibody... mehr
Produktinformationen "Anti-Smac / Diablo, clone RM271 (recombinant antibody)"
Antibody in PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide. This recombinant Smac antibody reacts to human Smac (Diablo homolog, mitochondrial). Protein function: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis- inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance. [The UniProt Consortium]
Schlagworte: Anti-Smac, Anti-SMAC, Anti-DIABLO, Anti-Diablo homolog, mitochondrial, Anti-Direct IAP-binding protein with low pI, Anti-Second mitochondria-derived activator of caspase, Recombinant Smac Antibody / Diablo
Hersteller: NSJ Bioreagents
Hersteller-Nr: R20288-0.1ML

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Monoclonal
Klon: RM271
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: A peptide corresponding to the C-terminus of human Smac/Diablo was used as the immunogen for this recombinant Smac antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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