Anti-SLC22A2

Anti-SLC22A2
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-62923.60 60 µl -

7 - 16 Werktage*

198,00 €
E-AB-62923.120 120 µl -

7 - 16 Werktage*

317,00 €
E-AB-62923.200 200 µl -

7 - 16 Werktage*

525,00 €
 
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are... mehr
Produktinformationen "Anti-SLC22A2"
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. Protein function: Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity. [The UniProt Consortium]
Schlagworte: Anti-OCT2, Anti-hOCT2, Anti-SLC22A2, Anti-Organic cation transporter 2, Anti-Solute carrier family 22 member 2, SLC22A2 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-62923

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, rat
Immunogen: Recombinant protein of human SLC22A2

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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