Anti-SLC19A1

Anti-SLC19A1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32093 100 µg - -

3 - 10 Werktage

503,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Solute carrier family 19 (folate... mehr
Produktinformationen "Anti-SLC19A1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Solute carrier family 19 (folate transporter), member 1, also known as SLC19A1 or RFC1, is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. And RFC1 plays a role in maintaining intracellular concentrations of folate. Protein function: Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump. [The UniProt Consortium]
Schlagworte: Anti-RFC, Anti-FOLT, Anti-FLOT1, Anti-IFC-1, Anti-SLC19A1, Anti-Folate transporter 1, Anti-Intestinal folate carrier 1, Anti-Placental folate transporter, Anti-Reduced folate carrier protein, Anti-Solute carrier family 19 member 1, SLC19A1 Antibody
Hersteller-Nr: R32093

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human
Immunogen: Amino acids FLKRPKRSLFFNRDDRGRCETSASELERMN of human SLC19A1 were used as the immunogen for the SLC19A1 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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