Anti-Siglec 1 (Sialic acid binding Ig-like lectin 1, Sialoadhesin, CD169, dJ1009E24.1, DKFZp667F058,

The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumors. Applications: Suitable for use in Western Blot, RIA, Flow Cytometry, ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (frozen): 1:10-1:2000, Immunohistochemistry (paraffin): 1:10-1:2000, Immunohistochemistry: 1:10-1:2000, Flow Cytometry: 1:10-1:1000, ELISA: 1:100-1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.