Anti-SARS-CoV-2 Surface Glycoprotein Rabbit Monoclonal Neutralizing (Clone 004)

Anti-SARS-CoV-2 Surface Glycoprotein Rabbit Monoclonal Neutralizing (Clone 004)
Anti-SARS-CoV-2 Surface Glycoprotein Rabbit Monoclonal Neutralizing (Clone 004)
   
COVID-19 Forschung
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay33627-100 100 µg -

6 - 10 Werktage*

736,00 €
 
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded... mehr
Produktinformationen "Anti-SARS-CoV-2 Surface Glycoprotein Rabbit Monoclonal Neutralizing (Clone 004)"
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of COVID-19. The SARS-CoV-2 surface glycoprotein, also known as the spike glycoprotein, is located on the outer envelope of the virion. It is composed of an S1 and S2 subunit divided by a furin S-cleavage site not found in other SARS-CoVs. The S1 subunit contains the receptor-binding domain (RBD), which binds to the carboxypeptidase angiotensin-converting enzyme 2 (ACE2), and the S1 and S2 subunits are cleaved by the protease TMPRSS2 to facilitate viral fusion with the host cell membrane. In this way, ACE2 acts as the functional receptor for SARS-CoV-2. SARS-CoV-2 infection can result in the production of neutralizing antibodies, which bind to the SARS-CoV-2 spike RBD preventing further viral entry and infection, starting approximately 4-10 days after symptom onset. Cayman's SARS-CoV-2 Surface Glycoprotein Rabbit Monoclonal Neutralizing Antibody (Clone 004) disrupts the S1-RBD-ACE2 interaction and can be used for ELISA.Synonyms: 2019-nCoV Spike Glycoprotein, 2019-nCoV Surface Glycoprotein, COVID-19 Spike Glycoprotein, COVID-19 Surface Glycoprotein, SARS-CoV-2 Spike Glycoprotein, Severe Acute Respiratory Syndrome Coronavirus 2 Surface Glycoprotein. Immunogen: Recombinant SARS-CoV-2 Surface Glycoprotein RBD-mFc Protein. Clone Designation: 004. Formulation: (Request formulation change), 100 µg of protein A-purified monoclonal antibody. Storage Buffer: 0.2 µm filtered solution in PBS. Host: HEK293 cells. Isotype: IgG. Applications: ELISA.
Schlagworte: 2019-nCoV Spike Glycoprotein, 2019-nCoV Surface Glycoprotein, COVID-19 Spike Glycoprotein, COVID-19 Surface Glycoprotein, SARS-CoV-2 Spike Glycoprotein, Severe Acute Respiratory Syndrome Coronavirus 2 Surface Glycoprotein
Hersteller: Cayman Chemical
Hersteller-Nr: 33627

Eigenschaften

Anwendung: ELISA
Antikörper-Typ: Monoclonal
Klon: 004
Konjugat: No
Wirt: Hek293 cells
Spezies-Reaktivität: SARS-CoV-2
Immunogen: Recombinant SARS-CoV-2 Surface Glycoprotein RBD-mFc Protein
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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