Anti-SAP97 / DLG1

Anti-SAP97 / DLG1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32206 100 µg - -

3 - 10 Werktage

503,00 €
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Disks large homolog 1 (DLG1), also known... mehr
Produktinformationen "Anti-SAP97 / DLG1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength. Protein function: Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. [The UniProt Consortium]
Schlagworte: Anti-hDlg, Anti-DLG1, Anti-SAP97, Anti-SAP-97, Anti-Disks large homolog 1, Anti-Synapse-associated protein 97, SAP97 Antibody / DLG1
Hersteller-Nr: R32206


Anwendung: WB, IHC (paraffin)
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Amino acids 1-165 of human SAP97 were used as the immunogen for the SAP97 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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