Anti-SAP102 / Synapse-associated protein 102

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Disks large homolog 3 (DLG3) also known as neuroendocrine-DLG or synapse-associated protein 102 (SAP-102) is a protein that in humans is encoded by the DLG3 gene. DLG3 is a member of the membrane-associated guanylate kinase (MAGUK) superfamily of proteins. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Protein function: Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. [The UniProt Consortium]