Anti-S1P1 (protein A-purified)

Anti-S1P1 (protein A-purified)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay20208-1 1 each -

6 - 10 Werktage*

422,00 €
 
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G protein-coupled... mehr
Produktinformationen "Anti-S1P1 (protein A-purified)"
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P1 primarily couples with pertussis toxin-sensitive Gi/o proteins to mediate S1P-induced cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Expression of S1P1 is abundant in embryological vasculature and is ubiquitously expressed in adult cells, suggesting diverse physiological functions of this receptor. The human and mouse S1P1 receptors have 382 amino acids with an estimated molecular weight of 43 kDa. Glycosylation at the N-terminal extracellular domain may cause the protein to migrate at a higher position in SDS-PAGE. Cayman's S1P1 Polyclonal Antibody (protein A-purified) can be used for western blot applications. The antibody recognizes S1P1 at 42 kDa from human, mouse, porcine, and rat samples.Synonyms: EDG-1, S1PR1, Sphingosine-1-phosphate Receptor 1. Immunogen: Peptide from the internal region of human S1P1. Formulation: (Request formulation change), 500 µl of protein-A purified polyclonal antibody. Storage Buffer: TBS, pH 7.4, with 50% glycerol, 0.1% BSA, and 0.02% sodium azide. Host: Rabbit. Applications: WB. UniProt Accession #: P21453.
Schlagworte: Anti-S1P1, Anti-S1P1, Anti-S1PR1, Anti-CD363, Anti-CD363, Anti-CHEDG1, Anti-S1P receptor 1, Anti-S1P receptor 1, Anti-S1P receptor Edg-1, Anti-S1P receptor Edg-1, Anti-Sphingosine 1-phosphate receptor 1, Anti-Sphingosine 1-phosphate receptor 1, Anti-Sphin
Hersteller: Cayman Chemical
Hersteller-Nr: 20208

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, swine, rat
Immunogen: Peptide from the internal region of human S1P1
MW: 42 kD
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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