Anti-S100 Calcium Binding Protein A12 (S100A12, CAAF1, Calcium-binding Protein in Amniotic Fluid, Ca

Anti-S100 Calcium Binding Protein A12 (S100A12, CAAF1, Calcium-binding Protein in Amniotic Fluid, Ca
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
S0051-88L.100 100 µl - -

3 - 19 Werktage*

498,00 €
 
S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs.... mehr
Produktinformationen "Anti-S100 Calcium Binding Protein A12 (S100A12, CAAF1, Calcium-binding Protein in Amniotic Fluid, Ca"
S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot 1:1000, Western blot, where a band is seen ~14 kD., Other applications have not been tested. Positive Controls: HeLa whole cell extract, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-Calcitermin, Anti-Protein S100-A12, Anti-Neutrophil S100 protein, Anti-S100 calcium-binding protein A12, Anti-Calcium-binding protein in amniotic fluid 1, Anti-Extracellular newly identified RAGE-binding protein
Hersteller: United States Biological
Hersteller-Nr: S0051-88L

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Full length human S100A12 protein [Swiss-Prot# P80511] expressed in E. coli. Cellular Localization: nuclear and cytoplasm.
Reinheit: Serum
Format: Serum

Datenbank Information

UniProt ID : P80511 | Finde Alternativen
Gene ID GeneID 6283 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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