Anti-REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (Azide free) (FITC)

Anti-REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (Azide free) (FITC)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
R1423-50E-FITC.200 200 µl - -

3 - 19 Werktage*

799,00 €
 
Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the... mehr
Produktinformationen "Anti-REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (Azide free) (FITC)"
Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NF-kB regulates the expression of a wide variety of genes that involved in apoptosis, viral life cycle, tumorigenesis, autoimmune diseases and inflammation. NF-kB is a heterodimer of members of the rel family of proteins such as p50, p65, and c-rel. In most cells, inhibitory IkB proteins sequester NF-kB/Rel in the cytoplasm. Cellular stimulation precipitates degradation of IkB and modification of NF-kB/Rel proteins, permitting translocation of NF-kB/Rel (c-Rel and RelA) to the nucleus for action on target genes. The important role of c-Rel in B-cell development, growth, and survival has been intensively studied, as well as its function in differentiation and lymphopoiesis (particularly lymphoid cancer). Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-REL, Anti-Proto-oncogene c-Rel
Hersteller: United States Biological
Hersteller-Nr: R1423-50E-FITC

Eigenschaften

Anwendung: FLISA, WB
Antikörper-Typ: Polyclonal
Konjugat: FITC
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: Synthetic peptide selected from the C-terminal region of human C-rel (NFkB) (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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