Anti-REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (Azide Free) (Bioti

Anti-REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (Azide Free) (Bioti
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
R1423-50E-Biotin.200 200 µl - -

3 - 19 Werktage*

993,00 €
 
Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the... mehr
Produktinformationen "Anti-REL, CT (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel) (Azide Free) (Bioti"
Nuclear factor (NF)-kappa B is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NF-kB regulates the expression of a wide variety of genes that involved in apoptosis, viral life cycle, tumorigenesis, autoimmune diseases and inflammation. NF-kB is a heterodimer of members of the rel family of proteins such as p50, p65, and c-rel. In most cells, inhibitory IkB proteins sequester NF-kB/Rel in the cytoplasm. Cellular stimulation precipitates degradation of IkB and modification of NF-kB/Rel proteins, permitting translocation of NF-kB/Rel (c-Rel and RelA) to the nucleus for action on target genes. The important role of c-Rel in B-cell development, growth, and survival has been intensively studied, as well as its function in differentiation and lymphopoiesis (particularly lymphoid cancer). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-REL, Anti-Proto-oncogene c-Rel
Hersteller: United States Biological
Hersteller-Nr: R1423-50E-Biotin

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: Biotin
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: Synthetic peptide selected from the C-terminal region of human C-rel (NFkB) (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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