Anti-PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)

Anti-PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
030572.100 100 µg - -

3 - 19 Werktage*

719,00 €
 
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products:... mehr
Produktinformationen "Anti-PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)"
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. Applications: Western Blot: 1:500-1:2000, Immunohistochemistry: 1:200-1:1000, Immunocytochemistry: 1:50-1:500, Flow Cytometry: 1:200-1:400, ELISA: 1:10000, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: Anti-GLBA, Anti-PSAP
Hersteller: United States Biological
Hersteller-Nr: 030572

Eigenschaften

Anwendung: ELISA, FC, ICC, IHC, WB
Antikörper-Typ: Monoclonal
Klon: 13B650
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. coli.

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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