Anti-Prohibitin 1 / PHB1, clone PHB/1881

Anti-Prohibitin 1 / PHB1, clone PHB/1881
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V3517-20UG 20 µg - -

3 - 10 Werktage*

332,00 €
NSJ-V3517-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. This antibody... mehr
Produktinformationen "Anti-Prohibitin 1 / PHB1, clone PHB/1881"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. This antibody recognizes a protein of 30kDa which is identified as Prohibitin (PHB), an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although PHB mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. It is an ideal mitochondrial marker. It shows anti-proliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. Protein function: Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. [The UniProt Consortium]
Schlagworte: Anti-PHB, Anti-Prohibitin, Prohibitin 1 Antibody / PHB1
Hersteller: NSJ Bioreagents
Hersteller-Nr: V3517

Eigenschaften

Anwendung: WB, IHC (paraffin), ELISA
Antikörper-Typ: Monoclonal
Klon: PHB/1881
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: A recombinant human partial protein corresponding to amino acids 167-261 was used as the immunogen for the Prohibitin antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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