Anti-PRKAG2

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA004246.25 25 µl -

Fragen Sie uns nach der Lieferzeit

156,00 €
ATA-HPA004246.100 100 µl -

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363,00 €
 
Protein function: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy... mehr
Produktinformationen "Anti-PRKAG2"
Protein function: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 84%
Schlagworte: Anti-PRKAG2, Anti-H91620p, Anti-AMPK gamma2, Anti-AMPK subunit gamma-2, Anti-5'-AMP-activated protein kinase subunit gamma-2
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA004246

Eigenschaften

Anwendung: ICC, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: STPTQVTKQH TFPLESYKHE PERLENRIYA SSSPPDTGQR FCPSSFQSPT RPPLASPTHY APSKAAALAA ALGPAEAGML EKLEFEDEAV EDSESGVYMR FMRSHK (ATA-APrEST86734)

Datenbank Information

KEGG ID : K07200 | Passende Produkte
UniProt ID : Q9UGJ0 | Passende Produkte
Gene ID : GeneID 51422 | Passende Produkte
Protein Atlas Nr. : ENSG00000106617

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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