Anti-PRKAG1

Anti-PRKAG1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-PACO17524.50 50 µl -

9 - 20 Werktage*

293,00 €
 
PRKAG1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and... mehr
Produktinformationen "Anti-PRKAG1"
PRKAG1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. PRKAG1 Antibody is a high quality polyclonal antibody for research use only.. Protein function: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive. [The UniProt Consortium]
Schlagworte: Anti-AMPKg, Anti-PRKAG1, Anti-AMPK gamma1, Anti-AMPK subunit gamma-1, Anti-5'-AMP-activated protein kinase subunit gamma-1
Hersteller: Assay Genie
Hersteller-Nr: PACO17524

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic peptide of human PRKAG1

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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