Anti-PRDX6

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ATA-HPA006983.100 100 µl -

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363,00 €
 
Protein function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and... mehr
Produktinformationen "Anti-PRDX6"
Protein function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (PubMed:9497358, PubMed:10893423). Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (PubMed:10893423). Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity) (PubMed:10893423, PubMed:26830860). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH (PubMed:10893423). Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis (PubMed:10893423). Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3- phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero- 3-phosphocholine or PC) (PubMed:26830860). Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate (PubMed:26830860). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 93%
Schlagworte: Anti-AOP2, Anti-PRDX6, Anti-NSGPx, Anti-aiPLA2, Anti-LPCAT-5, Anti-1-Cys PRX, Anti-24 kDa protein, Anti-Peroxiredoxin-6, Anti-1-Cys peroxiredoxin, Anti-Liver 2D page spot 40, Anti-Antioxidant protein 2, Anti-LPC acyltransferase 5
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA006983

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GGLLLGDVAP NFEANTTVGR IRFHDFLGDS WGILFSHPRD FTPVCTTELG RAAKLAPEFA KRNVKLIALS IDSVEDHLAW SKDINAYNCE EPTEKLPFPI IDDRNRELAI LLGMLDPAEK DEKGMPVTAR VVFVFGPDKK LKLSILYPA (ATA-APrEST70729)

Datenbank Information

KEGG ID : K11188 | Passende Produkte
UniProt ID : P30041 | Passende Produkte
Gene ID : GeneID 9588 | Passende Produkte
Protein Atlas Nr. : ENSG00000117592

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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