Anti-Phospho-ERBB2 (Y1112) (PACO02663)

Anti-Phospho-ERBB2 (Y1112) (PACO02663)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-PACO02663.50 50 µg - -

9 - 20 Werktage*

231,00 €
 
Phospho-ERBB2 (Y1112) Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for... mehr
Produktinformationen "Anti-Phospho-ERBB2 (Y1112) (PACO02663)"
Phospho-ERBB2 (Y1112) Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, WB applications. Phospho-ERBB2 (Y1112) Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. [The UniProt Consortium]
Schlagworte: Anti-phospho-HER2, Anti-phospho-ERBB2, Anti-phospho-CD340, Anti-phospho-MLN 19, Anti-phospho-p185erbB2, EC=2.7.10.1, Anti-phospho-Proto-oncogene Neu, Anti-phospho-Proto-oncogene c-ErbB-2, Anti-phospho-Metastatic lymph node gene 19 protein
Hersteller: Assay Genie
Hersteller-Nr: PACO02663

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: synthesized peptide derived from human Neu around the phosphorylation site of Y1112.
Formel: affinity purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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