Anti-PAX5

Anti-PAX5
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-65425.60 60 µl -

7 - 16 Werktage*

198,00 €
E-AB-65425.120 120 µl -

7 - 16 Werktage*

317,00 €
E-AB-65425.200 200 µl -

7 - 16 Werktage*

525,00 €
 
This gene encodes a member of the paired box (PAX) family of transcription factors. The central... mehr
Produktinformationen "Anti-PAX5"
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcri Protein function: May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. [The UniProt Consortium]
Schlagworte: Anti-PAX5, Anti-BSAP, Anti-Paired box protein Pax-5, Anti-B-cell-specific transcription factor, PAX5 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-65425

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant protein of human PAX5

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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