Anti-p300 (CREBBP/EP300 Inhibitory Protein 1, Cyclic AMP Responsive Enhancer Binding Protein, EP300:

Anti-p300 (CREBBP/EP300 Inhibitory Protein 1, Cyclic AMP Responsive Enhancer Binding Protein, EP300:
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
P1010-02A.200 200 µl - -

3 - 19 Werktage*

498,00 €
 
p300 is a relatively stable, ubiquitously expressed, nuclear phosphoprotein which is conserved... mehr
Produktinformationen "Anti-p300 (CREBBP/EP300 Inhibitory Protein 1, Cyclic AMP Responsive Enhancer Binding Protein, EP300:"
p300 is a relatively stable, ubiquitously expressed, nuclear phosphoprotein which is conserved among a variety of mammalian species. It is actively synthesized and phosphorylated in both quiescent and proliferating cells. Cyclic AMP-responsive enhancer binding protein (CREB) binding protein (CBP) and p300 are closely related transcriptional coactivators and have been shown to directly interact with many different DNA-binding transcription factors including nuclear hormone receptors, CREB, c-Fos, C-Jun/v-Jun, c-Myb/v-Myb, TFIIB and MyoD. Both CBP and p300 have been shown to display histone acetyltransferase (HAT) activity, capable of acetylating all four core histone particles in nucleosomes. As a result of HAT activity, it has been suggested CBP and p300 may play a direct role in activating chromatin for transcription. , Cellular Localization: Nuclear, Applications: Suitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Hersteller: United States Biological
Hersteller-Nr: P1010-02A

Eigenschaften

Anwendung: IF, IP, WB
Antikörper-Typ: Monoclonal
Klon: 9A256
Konjugat: No
Wirt: Mouse
Reaktivität: Human, Monkey, Mouse, Rat
Immunogen: Fusion protein containing residues 1572-2371 of human p300.
Reinheit: Purified by Protein G affinity chromatography.
Format: Affinity Purified

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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