Anti-OX40 / CD134

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32104 100 µg - -

3 - 10 Werktage

503,00 €
0.5mg/ml if reconstituted with 0.2ml sterile DI water. OX40 (CD134) and its binding partner,... mehr
Produktinformationen "Anti-OX40 / CD134"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between the proteins plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease. Protein function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. [The UniProt Consortium]
Schlagworte: Anti-CD134, Anti-TXGP1L, Anti-TNFRSF4, Anti-ACT35 antigen, Anti-OX40L receptor, Anti-Tumor necrosis factor receptor superfamily member 4, Anti-TAX transcriptionally-activated glycoprotein 1 receptor, OX40 Antibody / CD134
Hersteller-Nr: R32104


Anwendung: WB, IHC (paraffin), FC
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human
Immunogen: Amino acids AILLALYLLRRDQRLPPDAHKPP of human CD134/OX40
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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