Anti-NR2C2

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA006313.25 25 µl -

7 - 10 Werktage*

300,00 €
ATA-HPA006313.100 100 µl -

7 - 10 Werktage*

421,00 €
 
Protein function: Orphan nuclear receptor that can act as a repressor or activator of... mehr
Produktinformationen "Anti-NR2C2"
Protein function: Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior. Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 96%
Schlagworte: Anti-TAK1, Anti-NR2C2, Anti-Testicular receptor 4, Anti-Orphan nuclear receptor TR4, Anti-Orphan nuclear receptor TAK1, Anti-Nuclear receptor subfamily 2 group C member 2
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA006313

Eigenschaften

Anwendung: ICC, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DGARQTGLLD PGMLVNIQQP LIREDGTVLL ATDSKAETSQ GALGTLANVV TSLANLSESL NNGDTSEIQP EDQSASEITR AFDTLAKALN TTDSSSSPSL ADGIDTSGGG SIHVISRDQS TPIIEVEGPL LSDTHVTFKL TMPSPMP (ATA-APrEST70756)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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