Anti-NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,

Anti-NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
038937.200 200 µl - -

4 - 22 Werktage

557,00 €
 
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S... mehr
Produktinformationen "Anti-NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,"
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: Anti-NFKB1
Hersteller: United States Biological
Hersteller-Nr: 038937

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human
Immunogen: NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-938 amino acids from the C-terminal region of human NFKB(p105).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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