Anti-NAMPT

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA047776.100 100 µl -

7 - 10 Werktage*

358,00 €
 
Protein function: Catalyzes the condensation of nicotinamide with 5-... mehr
Produktinformationen "Anti-NAMPT"
Protein function: Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%
Schlagworte: Anti-PBEF, Anti-NAMPT, Anti-Nampt, Anti-Visfatin, Anti-NAmPRTase, Anti-Pre-B cell-enhancing factor, Anti-Pre-B-cell colony-enhancing factor 1, Anti-Nicotinamide phosphoribosyltransferase
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA047776

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: QETAGIGASA HLVNFKGTDT VAGLALIKKY YGTKDPVPGY SVPAAEHSTI TAWGKDHEKD AFEHIVTQFS SVPVSVVSDS YDIYNACEKI WGED (ATA-APrEST89085)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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