Anti-MKI67

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA000451.25 25 µl -

7 - 10 Werktage*

240,00 €
ATA-HPA000451.100 100 µl -

7 - 10 Werktage*

358,00 €
 
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm... mehr
Produktinformationen "Anti-MKI67"
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 66% and to rat: 67%
Schlagworte: Anti-Antigen Ki67, Anti-Antigen KI-67, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by monoclonal antibody Ki-67
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA000451

Eigenschaften

Anwendung: ICC, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PAKVEDAADS ATKPENLSSK TRGSIPTDVE VLPTETEIHN EPFLTLWLTQ VERKIQKDSL SKPEKLGTTA GQMCSGLPGL SSVDINNFGD SINESEGIPL KRRRVSFGGH LRPELFDENL PPNTPLKRGE APTKRKSLVM HTPPVLKKII K (ATA-APrEST79727)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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