Anti-mGluR5/1a

Anti-mGluR5/1a antibody is directed against GluR5/1a. GluR5/1a antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling is blocked by preadsorption of antibody with the peptide used as antigen to generate the antibody. The antibody is a total IgG fraction. Expect reactivity with the following species based on sequence homology: human, mouse, rat. Cross reactivity with mGluR5/1a from other species has not been determined. Protein function: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. [The UniProt Consortium]