Anti-MAP Kinase 3 (Mitogen-activated Protein Kinase 3, MAPK 3, MAPK3, ERT2, Extracellular Signal-reg

Anti-MAP Kinase 3 (Mitogen-activated Protein Kinase 3, MAPK 3, MAPK3, ERT2, Extracellular Signal-reg
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E3452-44A1.50 50 µg - -

1 - 19 Werktage

722,00 €
 
ERK1, a MAPK -type protein kinase, is a member of the Ras-MAPK pathway. This pathway modulates... mehr
Produktinformationen "Anti-MAP Kinase 3 (Mitogen-activated Protein Kinase 3, MAPK 3, MAPK3, ERT2, Extracellular Signal-reg"
ERK1, a MAPK -type protein kinase, is a member of the Ras-MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins, and other protein kinases, leading to biological responses such as cell proliferation and differentiation. Inactive ERK1 associates with MAPK/ERK kinases (MEK) 1 and 2 in the cytosol. Upon stimulation, MEK1/2 phosphorylates and activates ERK1 causing dissociation of the MEK/ERK complex. A portion of the activated ERK1 pool forms dimers and translocates to the nucleus to activate nuclear proteins such as ELK-1 and MSK1. Cytosolic ERK 1 acts on a different set of substrates, including MNK1/2 and MAPKAP-K1. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000, Immunofluorescence: 25ug/ml, Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hersteller: United States Biological
Hersteller-Nr: E3452-44A1

Eigenschaften

Anwendung: ELISA, IF, IHC, WB
Antikörper-Typ: Monoclonal
Klon: 3C9
Konjugat: No
Wirt: Mouse
Reaktivität: Human
Immunogen: Recombinant corresponding to aa279-379 from human MAPK3 with GST tag. MW of the GST tag alone is 26kD.
Reinheit: Purified by Protein A affinity chromatography.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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