Anti-MAP Kinase 14 (Thr180/Tyr182) (Mitogen-activated Protein Kinase 14, MAPK 14, MAPK14, Mitogen-ac

Anti-MAP Kinase 14 (Thr180/Tyr182) (Mitogen-activated Protein Kinase 14, MAPK 14, MAPK14, Mitogen-ac
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
M2352-03W-PE.200 200 µl - -

3 - 19 Werktage*

993,00 €
 
MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple... mehr
Produktinformationen "Anti-MAP Kinase 14 (Thr180/Tyr182) (Mitogen-activated Protein Kinase 14, MAPK 14, MAPK14, Mitogen-ac"
MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-CSBP, Anti-MAPK14, Anti-SAPK2a, Anti-MAPK 14, EC=2.7.11.24, Anti-MAP kinase 14, Anti-MAP kinase MXI2, Anti-MAP kinase p38 alpha, Anti-CSAID-binding protein, Anti-MAX-interacting protein 2, Anti-Stress-activated protein kinase 2a
Hersteller: United States Biological
Hersteller-Nr: M2352-03W-PE

Eigenschaften

Anwendung: FLISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: Synthetic non-phosphopeptide corresponding to amino acid residues surrounding Thr180 of human MAPK14 (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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