Anti-LBP (Lipopolysaccharide binding protein)

Anti-LBP (Lipopolysaccharide binding protein)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32693 100 µg - -

3 - 10 Werktage*

503,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Lipopolysaccharide Binding Protein is a... mehr
Produktinformationen "Anti-LBP (Lipopolysaccharide binding protein)"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Lipopolysaccharide Binding Protein is a protein that in humans is encoded by the LBP gene. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Protein function: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:7517398, PubMed:24120359). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359). [The UniProt Consortium]
Schlagworte: Anti-LBP, Anti-Lipopolysaccharide-binding protein, LBP Antibody (Lipopolysaccharide binding protein)
Hersteller: NSJ Bioreagents
Hersteller-Nr: R32693

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Amino acids L177-E446 from the human protein
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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